Job Details

Clinical Research Fellow

Reference Number
026971
Location
Gilmorehill Campus / Main Building
College / Service
COLLEGE OF MVLS
Department
RI INFECTION IMMUNITY & INFLAMMATION
Job Family
Clinical
Position Type
Full Time
Salary Range

Job Purpose

This is a 3 year post to facilitate clinical research experience and training to support a research project in translational medicine.  As such, it will be suitable for clinicians training in a number of relevant medical specialities, including inflammation and mucosal immunology. 
 
The research project will represent a unique opportunity to join the collaboration between leading UK academics and Glaxo Smith Kline (GSK). The successful candidate will join research teams at the University of Glasgow with the aim of completing their doctoral studies.  Projects offered include:
 
1. Understanding the contribution of myeloid biology to the perpetuation of inflammatory synovitis - views from active disease and remission
2. Unravelling the hierarchy of cellular subset recruitment into inflamed tissues using a series of pre-clinical models of chemokine receptor biology and to be translated thereafter into inflammatory tissue biopsies.
3. Investigating the contribution of cytokine hierarchies in mucosal tissues using novel organoid and 3D culture technologies
 
As a Clinical Research Fellow (CRF) this post will allow the development of research skills and production of data which will ultimately lead to the submission of a PhD degree. Although research will form the major component of this post, participation in associated clinical duties will be incorporated into the job plan.

Main Duties and Responsibilities

1. Plan, design and implement an appropriate research project, in conjunction with relevant investigators and collaborators leading towards a PhD 
2. Manage data handling and interpretation of research results and take the lead in writing papers for publication in appropriate peer-reviewed journals. 
3. Accumulate a significant body of data of the standard required for submission for examination for a PhD 
4. Collaborate with colleagues and participate in team meetings/discussions and departmental research group activities. 
5. Keep up to date with recent literature and advances in the field. 
6. Present work at internal and external seminars and national/ international conferences as appropriate to enhance the profile of the research group.
7. Write and submit applications for Ethics and Research Management approval, as appropriate and in conjunction with principal investigators (PIs). 
8. Supervise undergraduate and postgraduate student projects and contribute to the academic progress of students.   
9. Undertake clinical work under an NHS honorary contract, as detailed below. 
10. Engage in continuous professional development.
11. Contribute to the enhancement of the University’s international profile in line with the University’s Strategic Plan - Inspiring People – Changing the World http://www.gla.ac.uk/about/strategy/people/ 
 
These key tasks are not intended to be exhaustive but simply highlight a number of major tasks which the staff member may be reasonably expected to perform.

Knowledge, Qualifications, Skills and Experience

Knowledge/Qualifications
Essential:

A1. Primary medical qualification.
A2. GMC registration and licence to practice.
A3. Evidence of achievement of Foundation competences.
A4. Hold a training position (not necessarily with a training number).
A5. Demonstrable interest in immunology research.
A6. If relevant, NHS Deanery approval to undertake out of programme activity
 
Desirable:
B1. Possess National Training Number (NTN).
B2. BSc or equivalent intercalated degree (e.g. population science).
B3. Evidence of distinction in career to date, e.g. prizes, awards, bursaries.
 
Skills
Essential:

C1. Ability to interrogate data systematically.
C2. Appropriate IT skills.
C3. Capacity for originality and innovation.
C4. Excellent communication skills (both written and oral).
C5. Good interpersonal skills and ability to work constructively with staff at all levels.
C6. Proven academic track record.
C7. Enthusiasm for immunology research.
C8. Self-motivation and the ability to work as part of a team and independently.
C9. Ability to manage research projects.
 
Desirable:
D1. Ability to deliver research that can be published in leading academic publications.
D2. Successful record of writing and presenting research.
D3. Proactive and efficient administrative ability.
D4. Experience of statistical analysis
 
Experience
Essential:

E1. Evidence of some previous research experience.
E2. Experience and/or interest in clinical immunology research.
E3. Ability to contribute to a defined project and develop research potential
 
Desirable:
F1. Experience in undergraduate teaching or postgraduate teaching.
F2. Publication record

Job Features

Clinical Research Fellowships offer medical graduates the opportunity for training in a range of research methodologies relevant to modern biomedical research.  Most Clinical Fellows will undertake research training to consolidate career prospects, by participating in relevant research, which form part of a PhD. The post should make individuals competitive for future NHS teaching hospital appointments or Academic Lecturer / Clinician Scientist awards.
The Experimental Medicine Initiative to Explore New Therapies (EMINENT) is an MRC-Industry co-funded programme, which brings together investigators and researchers from University College London (UCL), the University of Cambridge, the University of Glasgow, the University of Newcastle, Imperial College London and GlaxoSmithKline (GSK) to undertake novel science that would not be possible outside such a cross-sector network. Academic researchers gain unprecedented access to GSK's unlicensed asset portfolio, via collaborative preclinical and experimental medicine studies aimed at enhancing the understanding of disease mechanisms and accelerating the development of novel therapeutics for patients in underserved disease areas.
 
The overarching aim of EMINENT is to deliver significant scientific progress, to understand disease mechanisms, and develop new therapeutic strategies. Impact and success will be assessed across three key areas: Scientific innovation, network cohesion, and building research capacity through creating a cadre of scientific and clinical leaders promoting the benefits of multiple partner clinical/ preclinical studies holding a rich base of knowledge and skills developed within the unique industrial-academic research environment of EMINENT.
 
Research Training
Clinical Research Fellows are encouraged to attend workshops and training in generic transferable skills organised by the College of Medical, Veterinary and Life Sciences Graduate School. Full details of the programme are available at  https://www.gla.ac.uk/colleges/mvls/graduateschool/currentstudents/postgraduateresearch/skillstraining/.   Regular attendance at, and contribution to, research group meetings is expected.
The successful applicant will have the opportunity to spend time embedded within GSK as well as working with academic collaborators. During the industrial placement applicants will pursue their project work in collaboration with the relevant GSK project teams, and gain an understanding of how science influences R&D decision making. The structured mentoring and training programme afforded by EMINENT will allow candidates to develop as academic clinicians enhanced with industry experience in designing and conducting experimental medicine studies. 
 
Higher Degrees
Clinical Research Fellows will undertake study towards a PhD, in the University of Glasgow. In addition to an academic supervisor, all postgraduate students will have an independent adviser. Either the adviser or supervisor must be a member of full-time University academic staff.
 
Clinical Work
An appropriate honorary grading will be sought from the relevant NHS Service. Clinical activities may be limited to those required for research training such as recruitment to conduct of clinical research and advancement of immunology care. However, limited additional clinical work is possible, subject to the agreement of the supervisor and NHS Services Clinical Director, with in-patient and out-patient experience in Medicine and relevant Specialties. Where any clinical activities of a Service nature extend beyond the usual working week, confirmation in advance of any such responsibilities and agreement on additional payments must be obtained from appropriate NHS Services management. The individual will have a contract with the NHS Services via the appropriate directorate/division, which will specify the agreed amount of clinical work and the level of remuneration. Since the funding for this post does not include an element for clinical training or NHS service work, any such clinical work must be arranged to avoid impacting substantially on research time.
 
Funding Sources
This post will be funded by a prestigious MRC – GSK collaboration. It will be awarded on the basis of individual career achievement to date and the likelihood of the fellow contributing to an effective, existing research team. As noted above, there may be opportunities for additional salary supplements providing NHS cover in Medicine and related specialties (by negotiation with local NHS management and subject to prioritisation of research). In relation to such supplements, the University will act as Paymaster only.
 
Research Training Base
The Clinical Research Fellow will be based within the Institute of Infection, Immunity and Inflammation in the Sir Graeme Davies Building at Gilmorehill campus. Travel to collaborating sites may be required.
 
Teaching
There will be no regular commitment to teaching but research fellows are encouraged to contribute to both problem-based learning and clinical teaching sessions for undergraduate medical students when research commitments allow.
 
Assessment of Progress
All those matriculated for Higher Degrees will be subject to the Postgraduate School of the College for progress monitoring. This is completed according to the regulations set down in the University Calendar.
Written progress reports on projects on a monthly basis.
Research in Progress presentations, at least annually, to the Institute.
Reports/manuscripts of results of clinical trials undertaken, as appropriate.
General assessment during clinical work and meetings.
Annual interview by independent assessors.
 
Future
Research fellows will either return to run-through training, or may become eligible for an academic training post. 
    
Informal Enquiries 
Any informal enquiries regarding this post may be directed to Professor Iain McInnes via email iain.mcinnes@glasgow.ac.uk
 
For further information on EMINENT go to: https://www.ucl.ac.uk/eminent-consortium/
 
For general enquiries on EMINENT please contact Dr Charlotte Summers, EMINENT Training Lead, via email cs493@medschl.cam.ac.uk

 To apply: Please send a cv and covering letter to Ms Liz McIntyre at cato@medschl.cam.ac.uk

 

Standard Terms & Conditions

 

To apply: Please send a cv and covering letter to Ms Liz McIntyre at cato@medschl.cam.ac.uk
 

Salary will be on the Clinical Research Fellow grade, £33,550 - £58,092 per annum. The post will carry an additional entitlement depending on "on-call" responsibilities. This banding payment is paid under a separate arrangement with the NHS for which the University acts as paymaster only.

This post has funding on a full time basis for 3 years.

This post is fixed-term, as a training post, under the Fixed-term Employees (prevention of Less Favourable Treatment) Regulations 2002 and will end within 6 months of the completion of specialist training.

Probationary Period:
All members of staff are contracted to a 6 month notice period.

Members of staff are normally eligible to contribute to the Universities' Superannuation Scheme (USS) and on appointment shall be deemed to be in membership of the scheme and contributions deducted accordingly, unless the University is advised in writing prior to the commencement of employment of a wish not to join." Further information regarding the scheme is available from the Superannuation Officer, who is also prepared to advise on questions relating to the transfer of Superannuation benefits. It may be possible, if the relevant NHS Superannuation Scheme Criteria are met, for appointees to remain in the NHS Superannuation Scheme while in this post.”

Protecting Vulnerable Groups Scheme

The post for which you are applying is considered ‘registered work’ in terms of the Protection of Vulnerable Groups Act. It requires the successful applicant to become a Protecting Vulnerable Groups (PVG) Scheme member prior to appointment. This check is necessary to ensure that the University of Glasgow fulfils its legal duties under the Act.

If you are successful in your application, the offer of employment will be subject to PVG Scheme membership. Further information is available at:
http://www.disclosurescotland.co.uk/pvg/pvg_index.html

Please note it is a criminal offence to apply for a child care position if you are on the Disqualified From Working with Children List.

All research and related activities, including grants, donations, clinical trials, contract research, consultancy and commercialisation are required to be managed through the University’s relevant processes (e.g. contractual and financial), in accordance with the University Court’s policies.

It is the University of Glasgow’s mission to foster an inclusive climate, which ensures equality in our working, learning, research and teaching environment.

We strongly endorse the principles of Athena SWAN, including a supportive and flexible working environment, with commitment from all levels of the organisation in promoting gender equality.

The University of Glasgow, charity number SC004401.

Vacancy Reference: 026971, Closing Date: 16 September 2019

 

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